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Associate Scientist –Molecular/Cell Biology/Immunology

Paris, Île-de-FranceFull-time
About the Job
HiFiBiO Therapeutics is an emerging multinational biotherapeutics company focused on the mobilization of human immune system to combat disease.  We integrate deep-rooted biological expertise with our comprehensive single-cell profiling technologies to rapidly discover and advance a pipeline of antibody drugs to treat cancer and autoimmune disorders. aspires to benefit patients through open-innovation partnerships with industry and academia. For more information, see our website at http://hifibio.com/.
Job Description:
The HiFiBiO Therapeutics EU site (Paris) is currently recruiting an Associate Scientist in molecular biology/cell biology/immunology to participate in our R&D and therapeutic programs. Essential responsibilities include:
  • Development of either/both cell-based and/or the nucleic acid assays.
  • Contribution to translation of cell-based and molecular biology assay into a droplet microfluidic format.
  • Optimization of droplet-based assays to the industrial robustness level and standards.
  • Identification of technical risks and limitations, troubleshooting.
  • Formulation and execution of technical plans to meet collaborators/customers’ requirements.
  • Providing technical resource for method development, transfer, data interpretation and optimisation.
  • Preparing and reviewing of QC SOPs, protocols, and reports related to product release, stability study, method validation
The successful candidate will be expected to work cross-functionally as part of interdisciplinary multi-project teams with colleagues in Cambridge, Paris, and China, as well as to interact with collaborators.
Qualifications and Skills:
  • Strong expertise and know-how in key areas of molecular/cellular biology in the context of immune profiling with the expectation she/he will collaborate with scientists to implement microdroplet assays (e.g. droplet-based sequencing) developed internally or in collaboration with HiFiBiO partners.
  • Excellent bench skills.
  • Experience in developing and troubleshooting novel molecular and cellular assays.
  • Good multi-tasking, time management and organizational skills are essential.
  • Proven experience working in cross-functional, global teams is preferred.
  • A team player, able to work collaboratively and interact effectively across interfaces of disciplines and expertise.
  • The candidate must have strong record keeping and oral/written communication skills in English, French is a plus.

Hands-on experience:
  • Assay development.
  • High Throughput, High Content Screening.
  • Single cell analytic approaches (droplet based is a plus), including RT and RT-PCR.
  • Cloning, sequencing, gene assembly, PCR, qPCR.
  • Cell culture.
  • Primary cells handling, T cell purification and characterization, functional assays.
  • Flow cytometry setup and optimization and/or fluorescent microscopy.
  • Master’s degree in molecular/cell biology/immunology or related field with at least 2 years of industry experience, or bachelor with > 4 years of industry experience.
  • The candidate should be a tenacious problem-solver as well as a great team player. You will be passionate about science, proactive, and well-organized. You should be capable of working independently to deliver high quality results according to industry standards. This is an impactful opportunity to pursue your career in a multinational innovative biotech, working at the leading edge of immuno-oncology and autoimmune disease therapy.
To be considered for this role, please submit your resume and a cover letter to k.franciszkiewicz(at)hifibio.com and m.hamze(at)hifibio.com with the job title in the subject.
    About HiFiBiO Therapeutics

    HiFiBiO Therapeutics is an emerging multinational company mobilizing the human immune system to combat disease and transform patient care. We integrate deep-rooted biological expertise, apply advanced single-cell profiling technologies and leverage open-innovation strategies to accelerate the development of a repertoire of innovative antibody drugs to treat cancer and autoimmune disorders.